Foundation & Clinic · Knoxville, Tennessee

Local impact.
Global reach.

Expert memory care and service for East Tennessee families, clinical research that contributes to worldwide progress against Alzheimer’s disease, and mentorship for the next generation of dementia-care professionals.

How to become a patientCall (865) 888-9494
Older adults spending time together outdoors
Foundation & clinicClinical care, research, and community connection.About the foundation
Already a patient? Forms, billing & visit informationExplore clinical research

Find your next step

Where would you
like to start?

Our services

Memory care and diagnostics.

Evaluation, diagnostic testing, and treatment for memory and cognitive concerns.

Explore our services
New patients

How to become a patient.

Referrals start with your primary care provider. See what to send and what to expect.

See referral information
Clinical research

Current studies.

Alzheimer’s clinical trials at TMDF, and what participation involves.

Explore our research
Dr. Monica Crane, Founder and Medical Director

Leadership

Dr. Monica Crane

Founder & Medical Director

A nationally recognized expert in dementia care, Dr. Crane founded TMDF and has served as principal investigator for 16 clinical and research trials, a driving force in bringing cutting-edge diagnostics and treatments to East Tennessee.

She trained at Yale University, Jefferson Medical College, and the University of Pennsylvania, and is an Assistant Professor of Medicine at the UT-Knoxville Graduate School of Medicine.

Read Dr. Crane’s full bio

Tennessee Memory Disorders Foundation

More than
a clinic.

TMDF is a 501(c)(3) nonprofit foundation. Beyond the exam room, we support caregivers, bring clinical trials to East Tennessee patients, and mentor the next generation of dementia-care professionals.

DonateAbout the foundation
  • 48student interns trained in 2025
  • 150caregivers served through our support group
  • 100+patients in clinical trials

Here in Knoxville

1400 Dowell Springs Boulevard
Upper Entrance · Suite 340
Knoxville, Tennessee 37909
Get directions (opens Google Maps in a new tab)

Office: (865) 888-9494
Fax: (865) 444-7672

Patient information

Before your visit

Patients must be accompanied by a family member or friend, and a first evaluation lasts about two hours. Cash payments are not accepted for patient services.

Before your visit

A quick note about payment.

Cash payments are not accepted for patient services, including copays and visit-related charges.

Please contact the office with questions before your appointment.

Website information is educational and does not replace individual medical advice. For a medical emergency, call 911.